ANCSLEEP BLOG

The Pros and Cons of Using Antihistamines for Sleep

Posted by Darian Dozier on Feb 8, 2025 12:21:00 PM

Canva Design DAGODF_0gqY

In today’s fast-paced world, getting a good night’s sleep can sometimes feel like an elusive goal. Many people turn to over-the-counter solutions to help them catch some zzz's, and one common choice is antihistamines. Originally designed to treat allergy symptoms, antihistamines are also known for their sedative effects, making them a popular option for those struggling with occasional insomnia. But is using antihistamines for sleep a good idea? Let's delve into the pros and cons of this approach.

What Are Antihistamines?

Antihistamines are medications that block histamine, a chemical in the body that’s involved in allergic reactions. By doing so, they help relieve symptoms like sneezing, itching, and runny nose. However, many antihistamines, especially first-generation types like diphenhydramine (found in Benadryl) and doxylamine (found in Unisom), have a side effect that can be beneficial for sleep: drowsiness.

How Antihistamines Promote Sleep

The sedative effect of antihistamines is due to their ability to cross the blood-brain barrier and inhibit histamine receptors in the brain that are involved in wakefulness. This can make you feel drowsy and help you fall asleep. For people who experience occasional sleeplessness, this effect can be a quick fix, allowing them to drift off when their usual sleep routine fails.

The Pros of Using Antihistamines for Sleep

1. Easily Accessible

One of the biggest advantages of using antihistamines for sleep is their availability. These medications are sold over the counter and are easy to obtain without a prescription.

2. Effective for Short-Term Use

For occasional sleeplessness, antihistamines can be effective. They can help you fall asleep faster and stay asleep longer, which is especially helpful if you’re dealing with temporary sleep disruptions due to stress, travel, or other factors.

3. Familiarity and Affordability

Antihistamines are widely used for allergies, so many people are familiar with them. They are also relatively inexpensive compared to other sleep aids, making them an accessible option for those in need of short-term relief.

The Cons of Using Antihistamines for Sleep

1. Tolerance and Dependency

One of the major drawbacks of using antihistamines for sleep is that your body can build up a tolerance to their sedative effects over time. This means you may need to take higher doses to achieve the same level of drowsiness, which can increase the risk of side effects. Additionally, while antihistamines are not considered addictive, some people may become psychologically dependent on them to sleep.

2. Next-Day Drowsiness

The sedative effects of antihistamines can linger into the next day, causing grogginess, difficulty concentrating, and impaired coordination. This “hangover” effect can be particularly problematic if you need to be alert and focused during the day.

3. Potential Side Effects

Antihistamines can cause a range of side effects, especially in older adults. These can include dry mouth, blurred vision, constipation, urinary retention, and confusion. Long-term use of antihistamines has also been linked to an increased risk of cognitive decline in older adults, making them a less ideal option for sustained use.

4. Not Addressing the Root Cause

Using antihistamines to fall asleep doesn’t address the underlying cause of your sleep problems. Whether it's stress, poor sleep hygiene, or a medical condition like sleep apnea, relying on antihistamines may mask the issue rather than help you resolve it.

5. Risk of Interaction with Other Medications

If you’re taking other medications, especially those that also cause drowsiness or have anticholinergic effects, combining them with antihistamines can increase the risk of adverse effects. It’s always a good idea to consult with a healthcare provider before using antihistamines for sleep if you’re on other medications.

When Should You Use Antihistamines for Sleep?

Antihistamines can be a helpful option for short-term sleep problems, such as when you’re dealing with jet lag or occasional insomnia due to stress. However, they should not be used as a long-term solution for chronic sleep issues. If you find yourself relying on antihistamines regularly to fall asleep, it’s time to evaluate your sleep habits and possibly seek medical advice.

Alternatives to Antihistamines for Sleep

If you’re looking for safer and more sustainable ways to improve your sleep, consider the following alternatives:

  • Improve Sleep Hygiene: Establish a consistent sleep schedule, create a relaxing bedtime routine, and make your sleep environment comfortable and conducive to rest.

  • Limit Stimulants: Avoid caffeine and electronic devices before bed, as these can interfere with your ability to fall asleep.

  • Try Natural Sleep Aids: Melatonin supplements, valerian root, and chamomile tea are popular natural alternatives that can promote relaxation and better sleep without the side effects of antihistamines.

  • Practice Relaxation Techniques: Meditation, deep breathing exercises, and progressive muscle relaxation can help calm your mind and prepare your body for sleep.

Conclusion

While antihistamines can be an effective short-term solution for occasional sleeplessness, they come with a range of potential downsides, particularly if used regularly. Before reaching for the antihistamines, consider whether other, more sustainable options might be better for improving your sleep. If sleep problems persist, it’s essential to address the underlying cause, whether through lifestyle changes, natural remedies, or professional help. Sleep is vital for your overall health, and finding the right approach will help you achieve the rest you need in the long run.

If you or someone you love are continuing to have sleeping trouble, that may be a sign of an underlying problem. Please click the orange button below to take a free online sleep test and talk with one of our sleep health professionals. 

Take a Free Online Sleep Test

 

Topics: sleep aids

Subscribe to Email Updates

Recent Posts

Posts by Topic

see all