---
title: "Common Medications That Cause Drowsiness: What to Know and How to Cope"
description: Discover common medications that cause drowsiness and learn practical tips to manage these side effects for a safer, more alert daily life.
image: https://info.ancsleep.com/hubfs/Canva%20images/Canva%20Design%20DAGWZAI6emk.png
---

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# ANCSLEEP BLOG

# Common Medications That Cause Drowsiness: What to Know and How to Cope

Posted by [Darian Dozier](https://info.ancsleep.com/blog/author/darian-dozier) on Apr 3, 2024 8:00:00 AM

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Many medications are known to cause drowsiness, a side effect that can impact daily life, work, and even safety. Understanding which medications may cause sleepiness and knowing how to manage these side effects can help people take their medication safely and effectively. Here’s an overview of some common medications that can cause drowsiness and tips for managing these effects.

##  Why Do Some Medications Cause Drowsiness?

Drowsiness can result from medications that act on the central nervous system, which includes the brain and spinal cord. These medications can slow down brain activity, reduce arousal, and produce calming effects. While drowsiness can be a desired effect for some medications (such as sleep aids), it can also be an unwanted side effect, especially when people need to stay alert.

## Common Medications Known to Cause Drowsiness

### [**Antihistamines**](https://info.ancsleep.com/blog/understanding-the-relationship-between-antihistamines-and-sleep)

- **Examples**: Diphenhydramine (Benadryl), Chlorpheniramine, Cetirizine (Zyrtec), and Loratadine (Claritin).
- **How They Work**: These drugs treat allergies by blocking histamine, a chemical in the body that causes allergic reactions. However, older antihistamines, especially first-generation ones like diphenhydramine, can cross the blood-brain barrier, causing sedation.
- **Tip**: Consider non-drowsy options, like loratadine, or take antihistamines at bedtime if they make you sleepy.

### [**Antidepressants**](https://info.ancsleep.com/blog/understanding-antidepressants-and-their-impact-on-sleep)

- **Examples**: Trazodone, Amitriptyline, and Doxepin.
- **How They Work**: Some antidepressants, especially tricyclic antidepressants and certain SSRIs, affect serotonin and norepinephrine levels, which can induce drowsiness. Trazodone is often prescribed specifically for its sedative properties in people who have trouble sleeping.
- **Tip**: If drowsiness interferes with daily activities, talk to your doctor about adjusting the timing of doses or trying a less sedating antidepressant.

### [A**ntipsychotics**](https://info.ancsleep.com/blog/exploring-the-benefits-of-traveling-for-better-sleep-0)

- **Examples**: Quetiapine (Seroquel), Olanzapine (Zyprexa), and Risperidone (Risperdal).
- **How They Work**: Antipsychotic medications are often used to manage symptoms of bipolar disorder, schizophrenia, and other mental health conditions. Many work by influencing dopamine levels in the brain, which can cause sedation as a side effect.
- **Tip**: Taking these medications at night may reduce daytime drowsiness. Always consult your doctor before changing your medication routine.

### [**Anti-Anxiety Medications**](https://info.ancsleep.com/blog/anti-anxiety-drugs-and-sleep-apnea)

- **Examples**: Lorazepam (Ativan), Diazepam (Valium), and Alprazolam (Xanax).
- **How They Work**: Many anti-anxiety medications are benzodiazepines, which depress the central nervous system to reduce anxiety. Unfortunately, this effect also commonly leads to drowsiness and can impair alertness.
- **Tip**: Avoid alcohol and be cautious when operating heavy machinery or driving, as combining benzodiazepines with other sedatives can increase drowsiness and risk of accidents.

### **Pain Relievers**

- **Examples**: [Opioids](https://info.ancsleep.com/blog/how-opiate-medications-effect-sleep-0) like Oxycodone, Hydrocodone, and Morphine.
- **How They Work**: Opioid medications bind to receptors in the brain and spinal cord, blocking pain signals and providing relief. However, they also depress the central nervous system, which can lead to significant drowsiness.
- **Tip**: Take pain relievers only as prescribed, and avoid alcohol or other sedatives while using opioids to reduce the risk of enhanced drowsiness or respiratory depression.

### **Muscle Relaxants**

- **Examples**: Cyclobenzaprine (Flexeril), Methocarbamol (Robaxin), and Baclofen.
- **How They Work**: Muscle relaxants relieve muscle spasms by acting on the central nervous system. However, this action can make people feel sleepy or fatigued.
- **Tip**: Take muscle relaxants before bed if possible, as they may interfere with daytime activities that require alertness.

### [**Sleep Medications**](https://info.ancsleep.com/blog/how-opiate-medications-effect-sleep-0-0)

- **Examples**: Zolpidem (Ambien), Eszopiclone (Lunesta), and Ramelteon (Rozerem).
- **How They Work**: Sleep aids are designed to induce drowsiness, making it easier to fall and stay asleep. However, some can cause lingering drowsiness the following morning, especially if taken too late at night or if they affect sleep quality.
- **Tip**: Only use sleep medications as prescribed, and avoid taking them too close to waking hours to reduce the chances of grogginess the next day.

## Tips for Managing Medication-Related Drowsiness

While some drowsiness is unavoidable with certain medications, a few strategies can help reduce the impact:

1. **Adjust the Timing**: Taking medications at night instead of during the day can help prevent drowsiness from interfering with daily activities. Check with your doctor before adjusting doses.
2. **Stay Hydrated and Nourished**: Dehydration and low blood sugar can worsen drowsiness, so drink water and eat balanced meals throughout the day.
3. **Avoid Alcohol**: Alcohol can increase the sedative effects of many medications, making drowsiness more intense and risky.
4. **Get Adequate Sleep**: Quality sleep can make a significant difference in how well your body handles medication side effects. Aim for 7-9 hours per night to support alertness during the day.
5. **Exercise Regularly**: Physical activity can boost your energy levels, improve mood, and help counterbalance medication-related drowsiness.
6. **Talk to Your Doctor**: If drowsiness persists or is severely impacting your life, your healthcare provider may adjust your dosage, prescribe an alternative, or suggest coping strategies tailored to your needs.

## Conclusion

Medication-related drowsiness can be a frustrating and sometimes challenging side effect to manage, but understanding which medications can cause drowsiness and implementing a few lifestyle changes can make a difference. Always consult your healthcare provider if drowsiness is interfering with your daily life, as they can help you find solutions that maintain your safety and well-being.

If you or someone you love is struggling with sleep, please click the orange button below to take a free online sleep test to talk with one of our sleep health professionals. 

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 Topics: [Sleep Medicine](https://info.ancsleep.com/blog/topic/sleep-medicine), [medication](https://info.ancsleep.com/blog/topic/medication)

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- [obesity and sleep (2)](https://info.ancsleep.com/blog/topic/obesity-and-sleep)
- [oversleeping (2)](https://info.ancsleep.com/blog/topic/oversleeping)
- [pajamas (2)](https://info.ancsleep.com/blog/topic/pajamas)
- [partner sleep (2)](https://info.ancsleep.com/blog/topic/partner-sleep)
- [ptsd (2)](https://info.ancsleep.com/blog/topic/ptsd)
- [ptsd and sleep (2)](https://info.ancsleep.com/blog/topic/ptsd-and-sleep)
- [restorative sleep (2)](https://info.ancsleep.com/blog/topic/restorative-sleep)
- [roommate sleep (2)](https://info.ancsleep.com/blog/topic/roommate-sleep)
- [screen time and sleep (2)](https://info.ancsleep.com/blog/topic/screen-time-and-sleep)
- [seizure (2)](https://info.ancsleep.com/blog/topic/seizure)
- [sleep and emotion (2)](https://info.ancsleep.com/blog/topic/sleep-and-emotion)
- [sleep habits (2)](https://info.ancsleep.com/blog/topic/sleep-habits)
- [sleep latency (2)](https://info.ancsleep.com/blog/topic/sleep-latency)
- [sleep therapy (2)](https://info.ancsleep.com/blog/topic/sleep-therapy)
- [sleepiness (2)](https://info.ancsleep.com/blog/topic/sleepiness)
- [sleeping fabrics (2)](https://info.ancsleep.com/blog/topic/sleeping-fabrics)
- [smart beds (2)](https://info.ancsleep.com/blog/topic/smart-beds)
- [social jet lag (2)](https://info.ancsleep.com/blog/topic/social-jet-lag)
- [social media (2)](https://info.ancsleep.com/blog/topic/social-media)
- [stroke and sleep (2)](https://info.ancsleep.com/blog/topic/stroke-and-sleep)
- [testosterone and sleep (2)](https://info.ancsleep.com/blog/topic/testosterone-and-sleep)
- [thyroid (2)](https://info.ancsleep.com/blog/topic/thyroid)
- [vitamin deficiency and sleep (2)](https://info.ancsleep.com/blog/topic/vitamin-deficiency-and-sleep)
- [weight loss and sleep (2)](https://info.ancsleep.com/blog/topic/weight-loss-and-sleep)
- [womens sleep (2)](https://info.ancsleep.com/blog/topic/womens-sleep)
- [Academics and sleep (1)](https://info.ancsleep.com/blog/topic/academics-and-sleep)
- [CKD (1)](https://info.ancsleep.com/blog/topic/ckd)
- [Cleaning (1)](https://info.ancsleep.com/blog/topic/cleaning)
- [Cortisol (1)](https://info.ancsleep.com/blog/topic/cortisol)
- [Crohn's Disease (1)](https://info.ancsleep.com/blog/topic/crohns-disease)
- [Dementia and sleep (1)](https://info.ancsleep.com/blog/topic/dementia-and-sleep)
- [Kidney disease (1)](https://info.ancsleep.com/blog/topic/kidney-disease)
- [Neuropathy (1)](https://info.ancsleep.com/blog/topic/neuropathy)
- [New Puppy (1)](https://info.ancsleep.com/blog/topic/new-puppy)
- [Peripheral neuropathy (1)](https://info.ancsleep.com/blog/topic/peripheral-neuropathy)
- [Pulmonology (1)](https://info.ancsleep.com/blog/topic/pulmonology)
- [RLS (1)](https://info.ancsleep.com/blog/topic/rls)
- [Reflux (1)](https://info.ancsleep.com/blog/topic/reflux)
- [SRPE (1)](https://info.ancsleep.com/blog/topic/srpe)
- [Sleep Talking (1)](https://info.ancsleep.com/blog/topic/sleep-talking)
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- [Sleep related painful erections (1)](https://info.ancsleep.com/blog/topic/sleep-related-painful-erections)
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- [acid reflux (1)](https://info.ancsleep.com/blog/topic/acid-reflux)
- [addiction and sleep (1)](https://info.ancsleep.com/blog/topic/addiction-and-sleep)
- [adjustable beds (1)](https://info.ancsleep.com/blog/topic/adjustable-beds)
- [ai and sleep (1)](https://info.ancsleep.com/blog/topic/ai-and-sleep)
- [all nighter (1)](https://info.ancsleep.com/blog/topic/all-nighter)
- [altitude (1)](https://info.ancsleep.com/blog/topic/altitude)
- [alzheimers and sleep (1)](https://info.ancsleep.com/blog/topic/alzheimers-and-sleep)
- [anemia and fatigue (1)](https://info.ancsleep.com/blog/topic/anemia-and-fatigue)
- [antioxidants (1)](https://info.ancsleep.com/blog/topic/antioxidants)
- [antipsychotics (1)](https://info.ancsleep.com/blog/topic/antipsychotics)
- [aromatherapy and sleep (1)](https://info.ancsleep.com/blog/topic/aromatherapy-and-sleep)
- [arthritis and sleep (1)](https://info.ancsleep.com/blog/topic/arthritis-and-sleep)
- [artificial intelligence and sleep (1)](https://info.ancsleep.com/blog/topic/artificial-intelligence-and-sleep)
- [autism and sleep (1)](https://info.ancsleep.com/blog/topic/autism-and-sleep)
- [back pain (1)](https://info.ancsleep.com/blog/topic/back-pain)
- [back pain and sleep (1)](https://info.ancsleep.com/blog/topic/back-pain-and-sleep)
- [bipap (1)](https://info.ancsleep.com/blog/topic/bipap)
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- [burnout (1)](https://info.ancsleep.com/blog/topic/burnout)
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- [cbti (1)](https://info.ancsleep.com/blog/topic/cbti)
- [cerebral palsy and sleep (1)](https://info.ancsleep.com/blog/topic/cerebral-palsy-and-sleep)
- [chronic kidney disease (1)](https://info.ancsleep.com/blog/topic/chronic-kidney-disease)
- [climate and sleep (1)](https://info.ancsleep.com/blog/topic/climate-and-sleep)
- [cluster headache and sleep (1)](https://info.ancsleep.com/blog/topic/cluster-headache-and-sleep)
- [college students (1)](https://info.ancsleep.com/blog/topic/college-students)
- [cosleeping (1)](https://info.ancsleep.com/blog/topic/cosleeping)
- [cpap alternatives (1)](https://info.ancsleep.com/blog/topic/cpap-alternatives)
- [daytime fatigue (1)](https://info.ancsleep.com/blog/topic/daytime-fatigue)
- [decision-making and sleep (1)](https://info.ancsleep.com/blog/topic/decision-making-and-sleep)
- [desert sleep (1)](https://info.ancsleep.com/blog/topic/desert-sleep)
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- [dry climate and sleep (1)](https://info.ancsleep.com/blog/topic/dry-climate-and-sleep)
- [eczema and sleep (1)](https://info.ancsleep.com/blog/topic/eczema-and-sleep)
- [epworth sleep scale (1)](https://info.ancsleep.com/blog/topic/epworth-sleep-scale)
- [essential oils (1)](https://info.ancsleep.com/blog/topic/essential-oils)
- [estrogen and sleep (1)](https://info.ancsleep.com/blog/topic/estrogen-and-sleep)
- [excessive daytime sleepiness (1)](https://info.ancsleep.com/blog/topic/excessive-daytime-sleepiness)
- [face shape and sleep (1)](https://info.ancsleep.com/blog/topic/face-shape-and-sleep)
- [family sleep health (1)](https://info.ancsleep.com/blog/topic/family-sleep-health)
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- [fibroids and sleep (1)](https://info.ancsleep.com/blog/topic/fibroids-and-sleep)
- [fibromyalgia (1)](https://info.ancsleep.com/blog/topic/fibromyalgia)
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- [focus and sleep (1)](https://info.ancsleep.com/blog/topic/focus-and-sleep)
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- [heart failure (1)](https://info.ancsleep.com/blog/topic/heart-failure)
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- [high blood pressure and sleep (1)](https://info.ancsleep.com/blog/topic/high-blood-pressure-and-sleep)
- [hot flashes and sleep (1)](https://info.ancsleep.com/blog/topic/hot-flashes-and-sleep)
- [hypervigilence and sleep (1)](https://info.ancsleep.com/blog/topic/hypervigilence-and-sleep)
- [hypoglycemia (1)](https://info.ancsleep.com/blog/topic/hypoglycemia)
- [inflammation (1)](https://info.ancsleep.com/blog/topic/inflammation)
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- [light therapy (1)](https://info.ancsleep.com/blog/topic/light-therapy)
- [liver disease (1)](https://info.ancsleep.com/blog/topic/liver-disease)
- [metabolic syndrome and sleep (1)](https://info.ancsleep.com/blog/topic/metabolic-syndrome-and-sleep)
- [microsleep (1)](https://info.ancsleep.com/blog/topic/microsleep)
- [middle age (1)](https://info.ancsleep.com/blog/topic/middle-age)
- [midnight awakenings (1)](https://info.ancsleep.com/blog/topic/midnight-awakenings)
- [migraine (1)](https://info.ancsleep.com/blog/topic/migraine)
- [morning fatigue (1)](https://info.ancsleep.com/blog/topic/morning-fatigue)
- [mouthguards and sleep (1)](https://info.ancsleep.com/blog/topic/mouthguards-and-sleep)
- [multiple sclerosis (1)](https://info.ancsleep.com/blog/topic/multiple-sclerosis)
- [muscle tension and sleep (1)](https://info.ancsleep.com/blog/topic/muscle-tension-and-sleep)
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- [nighttime affirmations (1)](https://info.ancsleep.com/blog/topic/nighttime-affirmations)
- [nighttime awakenings (1)](https://info.ancsleep.com/blog/topic/nighttime-awakenings)
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- [nighttime worry (1)](https://info.ancsleep.com/blog/topic/nighttime-worry)
- [ocd and sleep (1)](https://info.ancsleep.com/blog/topic/ocd-and-sleep)
- [outdoor sleep (1)](https://info.ancsleep.com/blog/topic/outdoor-sleep)
- [oxytocin and sleep (1)](https://info.ancsleep.com/blog/topic/oxytocin-and-sleep)
- [parent (1)](https://info.ancsleep.com/blog/topic/parent)
- [parenting (1)](https://info.ancsleep.com/blog/topic/parenting)
- [peripheral vascular disease and sleep (1)](https://info.ancsleep.com/blog/topic/peripheral-vascular-disease-and-sleep)
- [phones and sleep (1)](https://info.ancsleep.com/blog/topic/phones-and-sleep)
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- [poor sleep (1)](https://info.ancsleep.com/blog/topic/poor-sleep)
- [posture and sleep (1)](https://info.ancsleep.com/blog/topic/posture-and-sleep)
- [progesterone and sleep (1)](https://info.ancsleep.com/blog/topic/progesterone-and-sleep)
- [protein and sleep (1)](https://info.ancsleep.com/blog/topic/protein-and-sleep)
- [psych (1)](https://info.ancsleep.com/blog/topic/psych)
- [reading and sleep (1)](https://info.ancsleep.com/blog/topic/reading-and-sleep)
- [recovery and sleep (1)](https://info.ancsleep.com/blog/topic/recovery-and-sleep)
- [remote workers (1)](https://info.ancsleep.com/blog/topic/remote-workers)
- [reproductivity and sleep (1)](https://info.ancsleep.com/blog/topic/reproductivity-and-sleep)
- [retirement and sleep (1)](https://info.ancsleep.com/blog/topic/retirement-and-sleep)
- [revenge bedtime procrastination (1)](https://info.ancsleep.com/blog/topic/revenge-bedtime-procrastination)
- [school and sleep (1)](https://info.ancsleep.com/blog/topic/school-and-sleep)
- [sciatica and sleep (1)](https://info.ancsleep.com/blog/topic/sciatica-and-sleep)
- [sedentary lifestyle and sleep (1)](https://info.ancsleep.com/blog/topic/sedentary-lifestyle-and-sleep)
- [sids (1)](https://info.ancsleep.com/blog/topic/sids)
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- [sleep and appetite (1)](https://info.ancsleep.com/blog/topic/sleep-and-appetite)
- [sleep and empathy (1)](https://info.ancsleep.com/blog/topic/sleep-and-empathy)
- [sleep and executive functioning (1)](https://info.ancsleep.com/blog/topic/sleep-and-executive-functioning)
- [sleep and mood (1)](https://info.ancsleep.com/blog/topic/sleep-and-mood)
- [sleep and outlook (1)](https://info.ancsleep.com/blog/topic/sleep-and-outlook)
- [sleep and self-perception (1)](https://info.ancsleep.com/blog/topic/sleep-and-self-perception)
- [sleep and stroke (1)](https://info.ancsleep.com/blog/topic/sleep-and-stroke)
- [sleep and temperature (1)](https://info.ancsleep.com/blog/topic/sleep-and-temperature)
- [sleep and trauma (1)](https://info.ancsleep.com/blog/topic/sleep-and-trauma)
- [sleep and work (1)](https://info.ancsleep.com/blog/topic/sleep-and-work)
- [sleep doctors (1)](https://info.ancsleep.com/blog/topic/sleep-doctors)
- [sleep drive (1)](https://info.ancsleep.com/blog/topic/sleep-drive)
- [sleep inertia (1)](https://info.ancsleep.com/blog/topic/sleep-inertia)
- [sleep influencers (1)](https://info.ancsleep.com/blog/topic/sleep-influencers)
- [sleep score (1)](https://info.ancsleep.com/blog/topic/sleep-score)
- [sleepwear (1)](https://info.ancsleep.com/blog/topic/sleepwear)
- [snacks (1)](https://info.ancsleep.com/blog/topic/snacks)
- [snooze (1)](https://info.ancsleep.com/blog/topic/snooze)
- [social media and sleep (1)](https://info.ancsleep.com/blog/topic/social-media-and-sleep)
- [somniphobia (1)](https://info.ancsleep.com/blog/topic/somniphobia)
- [stimulants and sleep (1)](https://info.ancsleep.com/blog/topic/stimulants-and-sleep)
- [substance abuse and sleep (1)](https://info.ancsleep.com/blog/topic/substance-abuse-and-sleep)
- [supplements (1)](https://info.ancsleep.com/blog/topic/supplements)
- [teeth grinding at night (1)](https://info.ancsleep.com/blog/topic/teeth-grinding-at-night)
- [tension headache and sleep (1)](https://info.ancsleep.com/blog/topic/tension-headache-and-sleep)
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- [untreated sleep apnea (1)](https://info.ancsleep.com/blog/topic/untreated-sleep-apnea)
- [vaping and sleep (1)](https://info.ancsleep.com/blog/topic/vaping-and-sleep)
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- [yawn (1)](https://info.ancsleep.com/blog/topic/yawn)
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[see all](https://info.ancsleep.com/blog/common-medications-that-cause-drowsiness-what-to-know-and-how-to-cope#)

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