---
title: Major Considerations for Melatonin Use
description: Melatonin can be a great sleep aid for short-term use, but long-term use can be problematic. Here are some considerations before taking the supplement.
image: https://info.ancsleep.com/hubfs/Canva%20images/Add%20a%20heading-Feb-06-2022-12-30-03-72-AM.png
---

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# ANCSLEEP BLOG

# Major Considerations for Melatonin Use

Posted by [Darian Dozier](https://info.ancsleep.com/blog/author/darian-dozier) on May 25, 2022 3:31:00 PM

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Melatonin is a natural hormone that is produced by the body at night. It is controlled by the amount of light that is allowed into the eye. It helps the body wind down and get ready for bed. Sometimes, when the body does not produce enough melatonin, there are exogenous options, or melatonin pills, that can help those who are having trouble falling asleep. However, those supplements come with some potential problems, of which you need to be aware. Continue reading to find out some things about melatonin that should give you pause before depending heavily on that supplement for good sleep. 

## Assuming natural = safe 

Melatonin is a hormone that is produced by the pineal gland in the brain. Whenever your retina, a group of cells in the back of your eye, senses that there is very little light (indicating nighttime), your brain will begin secreting melatonin. This hormone signals to your brain that it's time to go to sleep. 

Sometimes, this may be defective, or the amount of melatonin released is not enough to override the other factors that may be keeping you awake (i.e., stress, environmental disturbances, sleep disorders, etc.). Therefore, some will turn towards the supplement version of melatonin with an overreliance on the fact that, because it is natural, it's presumed safe. 

Melatonin is a natural hormone; however, in its exogenous form, it does not mean that it is safe for overconsumption. Your body uses a negative feedback system to control the amount of melatonin released at one time. This means that when melatonin is produced and exerts its effects on the rest of your body, it will provide a negative feedback to your brain to stop producing melatonin. 

When you take it exogenously, this feedback doesn't happen, which means melatonin could overreact in your body. Make sure to read the label of the dosing and try to adhere to the recommended amounts. 

## It's not a permanent solution for sleep 

Melatonin is not a cure-all for a lack of sleep. Better sleep habits and addressing underlying factors for poor sleep are what will increase your sleep in the long run. Melatonin is designed to be a short-term sleep aid.

Certain populations may benefit from more frequent doses, such as shift workers with irregular schedules, jet lag, and those with intermittent insomnia. However, for consistent and persistent sleep troubles, melatonin is not a permanent solution. 

You should talk with your health provider before taking melatonin to decide if it's really necessary and its safety profile. If there are underlying issues that are keeping you from sleeping, melatonin may mask them, leading to much worse issues. 

## It's not regulated 

Prescription drugs are regulated by the FDA and must go through many trials before they can be brought to market. Supplements, however, are not as regulated, meaning their labels don't have to be as exact as pharmaceuticals. The FDA also doesn't check to see how efficacious the supplement is or its safe dosing requirements. 

A study in 2017 found that melatonin supplements and the amount of melatonin they contained varied widely from what was on the label. Also, serotonin was detected in 26% of the samples analyzed. This means if you're taking other medications, such as Selective Serotonin Reuptake Inhibitors (SSRIs), then this could interfere and lead to serotonin syndrome. 

Before picking up a new supplement, do some research on any complaints or weird side effects other users have had from that brand. And most importantly, talk with your physician about which supplements they recommend. 

## It can lead to uncomfortable side effects 

Melatonin may help you sleep better; however, there are so many side effects that accompany it. Nausea, dizziness, headache, and drowsiness are all reported side effects. Therefore, it's important that after you take melatonin, you don't operate heavy machinery or drive. It's best to be in a safe location where you can fall asleep or one that doesn't require your alert attention. 

The following morning, it is possible that you will still feel drowsy or sleepy, so you may want to reconsider taking melatonin if you have to be up early or have something that requires your full attention. 

## Dangerous interactions are possible

Melatonin can have severe drug-drug interactions. This means that if you are taking a prescription medication, this supplement could negatively interfere with that. This is why it's so important to talk with your doctor, who is familiar with your medications. If they are aware of the drugs that you are taking, then they can provide you with some recommendations on whether melatonin is safe, and if so, how much and what brand. 

It's best to steer clear of melatonin if you have chronic insomnia or a severe sleep disorder like restless legs syndrome (RLS). Chronic insomnia can be treated more effectively with lifestyle remedies and cognitive behavioral therapy, as melatonin is not safe enough, per the lack of evidence, for long-term use. 

RLS is a disorder characterized by tingly feelings all over your legs and arms that can only be relieved by moving your legs. If you have been diagnosed with RLS, melatonin can increase your symptoms because it lowers the amount of dopamine in the blood. 

Dementia is another diagnosis in which you should steer clear of melatonin. The progressive deterioration is associated with insomnia, but melatonin can do more harm than good. It can increase the risk of falls and may result in daytime drowsiness. 

It's also not safe to consume melatonin if you have been drinking alcohol, are pregnant, or breastfeeding. 

## Alternatives to melatonin 

Sleep is very important, so if you are having trouble getting adequate sleep, then you must find great alternatives other than a reliance on melatonin. 

One way to improve your sleep is to improve your sleep hygiene. This consists of your sleep routine, sleep environment, and other behaviors that can negatively influence your ability to get a good night's rest (too much caffeine, late-night eating or working out, alcohol, etc.). 

If you continue to have trouble sleeping, please click the orange button below to talk with a sleep health professional from our facility! 

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https://alaskaregional.com/blog/entry/4-reasons-to-be-cautious-about-melatonin

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- [restorative sleep (2)](https://info.ancsleep.com/blog/topic/restorative-sleep)
- [roommate sleep (2)](https://info.ancsleep.com/blog/topic/roommate-sleep)
- [screen time and sleep (2)](https://info.ancsleep.com/blog/topic/screen-time-and-sleep)
- [seizure (2)](https://info.ancsleep.com/blog/topic/seizure)
- [sleep and emotion (2)](https://info.ancsleep.com/blog/topic/sleep-and-emotion)
- [sleep habits (2)](https://info.ancsleep.com/blog/topic/sleep-habits)
- [sleep latency (2)](https://info.ancsleep.com/blog/topic/sleep-latency)
- [sleep therapy (2)](https://info.ancsleep.com/blog/topic/sleep-therapy)
- [sleepiness (2)](https://info.ancsleep.com/blog/topic/sleepiness)
- [sleeping fabrics (2)](https://info.ancsleep.com/blog/topic/sleeping-fabrics)
- [smart beds (2)](https://info.ancsleep.com/blog/topic/smart-beds)
- [social jet lag (2)](https://info.ancsleep.com/blog/topic/social-jet-lag)
- [social media (2)](https://info.ancsleep.com/blog/topic/social-media)
- [stroke and sleep (2)](https://info.ancsleep.com/blog/topic/stroke-and-sleep)
- [testosterone and sleep (2)](https://info.ancsleep.com/blog/topic/testosterone-and-sleep)
- [thyroid (2)](https://info.ancsleep.com/blog/topic/thyroid)
- [vitamin deficiency and sleep (2)](https://info.ancsleep.com/blog/topic/vitamin-deficiency-and-sleep)
- [weight loss and sleep (2)](https://info.ancsleep.com/blog/topic/weight-loss-and-sleep)
- [womens sleep (2)](https://info.ancsleep.com/blog/topic/womens-sleep)
- [Academics and sleep (1)](https://info.ancsleep.com/blog/topic/academics-and-sleep)
- [CKD (1)](https://info.ancsleep.com/blog/topic/ckd)
- [Cleaning (1)](https://info.ancsleep.com/blog/topic/cleaning)
- [Cortisol (1)](https://info.ancsleep.com/blog/topic/cortisol)
- [Crohn's Disease (1)](https://info.ancsleep.com/blog/topic/crohns-disease)
- [Dementia and sleep (1)](https://info.ancsleep.com/blog/topic/dementia-and-sleep)
- [Kidney disease (1)](https://info.ancsleep.com/blog/topic/kidney-disease)
- [Neuropathy (1)](https://info.ancsleep.com/blog/topic/neuropathy)
- [New Puppy (1)](https://info.ancsleep.com/blog/topic/new-puppy)
- [Peripheral neuropathy (1)](https://info.ancsleep.com/blog/topic/peripheral-neuropathy)
- [Pulmonology (1)](https://info.ancsleep.com/blog/topic/pulmonology)
- [RLS (1)](https://info.ancsleep.com/blog/topic/rls)
- [Reflux (1)](https://info.ancsleep.com/blog/topic/reflux)
- [SRPE (1)](https://info.ancsleep.com/blog/topic/srpe)
- [Sleep Talking (1)](https://info.ancsleep.com/blog/topic/sleep-talking)
- [Sleep and Eyesight (1)](https://info.ancsleep.com/blog/topic/sleep-and-eyesight)
- [Sleep related painful erections (1)](https://info.ancsleep.com/blog/topic/sleep-related-painful-erections)
- [Ulcerative Colitis (1)](https://info.ancsleep.com/blog/topic/ulcerative-colitis)
- [acid reflux (1)](https://info.ancsleep.com/blog/topic/acid-reflux)
- [addiction and sleep (1)](https://info.ancsleep.com/blog/topic/addiction-and-sleep)
- [adjustable beds (1)](https://info.ancsleep.com/blog/topic/adjustable-beds)
- [ai and sleep (1)](https://info.ancsleep.com/blog/topic/ai-and-sleep)
- [all nighter (1)](https://info.ancsleep.com/blog/topic/all-nighter)
- [altitude (1)](https://info.ancsleep.com/blog/topic/altitude)
- [alzheimers and sleep (1)](https://info.ancsleep.com/blog/topic/alzheimers-and-sleep)
- [anemia and fatigue (1)](https://info.ancsleep.com/blog/topic/anemia-and-fatigue)
- [antioxidants (1)](https://info.ancsleep.com/blog/topic/antioxidants)
- [antipsychotics (1)](https://info.ancsleep.com/blog/topic/antipsychotics)
- [aromatherapy and sleep (1)](https://info.ancsleep.com/blog/topic/aromatherapy-and-sleep)
- [arthritis and sleep (1)](https://info.ancsleep.com/blog/topic/arthritis-and-sleep)
- [artificial intelligence and sleep (1)](https://info.ancsleep.com/blog/topic/artificial-intelligence-and-sleep)
- [autism and sleep (1)](https://info.ancsleep.com/blog/topic/autism-and-sleep)
- [back pain (1)](https://info.ancsleep.com/blog/topic/back-pain)
- [back pain and sleep (1)](https://info.ancsleep.com/blog/topic/back-pain-and-sleep)
- [bipap (1)](https://info.ancsleep.com/blog/topic/bipap)
- [bipolar disorder and sleep (1)](https://info.ancsleep.com/blog/topic/bipolar-disorder-and-sleep)
- [breastfeeding and sleep (1)](https://info.ancsleep.com/blog/topic/breastfeeding-and-sleep)
- [burnout (1)](https://info.ancsleep.com/blog/topic/burnout)
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- [cbti (1)](https://info.ancsleep.com/blog/topic/cbti)
- [cerebral palsy and sleep (1)](https://info.ancsleep.com/blog/topic/cerebral-palsy-and-sleep)
- [chronic kidney disease (1)](https://info.ancsleep.com/blog/topic/chronic-kidney-disease)
- [climate and sleep (1)](https://info.ancsleep.com/blog/topic/climate-and-sleep)
- [cluster headache and sleep (1)](https://info.ancsleep.com/blog/topic/cluster-headache-and-sleep)
- [college students (1)](https://info.ancsleep.com/blog/topic/college-students)
- [cosleeping (1)](https://info.ancsleep.com/blog/topic/cosleeping)
- [cpap alternatives (1)](https://info.ancsleep.com/blog/topic/cpap-alternatives)
- [daytime fatigue (1)](https://info.ancsleep.com/blog/topic/daytime-fatigue)
- [decision-making and sleep (1)](https://info.ancsleep.com/blog/topic/decision-making-and-sleep)
- [desert sleep (1)](https://info.ancsleep.com/blog/topic/desert-sleep)
- [dialysis and fatigue (1)](https://info.ancsleep.com/blog/topic/dialysis-and-fatigue)
- [digestion and sleep (1)](https://info.ancsleep.com/blog/topic/digestion-and-sleep)
- [doomscrolling and sleep (1)](https://info.ancsleep.com/blog/topic/doomscrolling-and-sleep)
- [drowsy teen driving (1)](https://info.ancsleep.com/blog/topic/drowsy-teen-driving)
- [dry climate and sleep (1)](https://info.ancsleep.com/blog/topic/dry-climate-and-sleep)
- [eczema and sleep (1)](https://info.ancsleep.com/blog/topic/eczema-and-sleep)
- [epworth sleep scale (1)](https://info.ancsleep.com/blog/topic/epworth-sleep-scale)
- [essential oils (1)](https://info.ancsleep.com/blog/topic/essential-oils)
- [estrogen and sleep (1)](https://info.ancsleep.com/blog/topic/estrogen-and-sleep)
- [excessive daytime sleepiness (1)](https://info.ancsleep.com/blog/topic/excessive-daytime-sleepiness)
- [face shape and sleep (1)](https://info.ancsleep.com/blog/topic/face-shape-and-sleep)
- [family sleep health (1)](https://info.ancsleep.com/blog/topic/family-sleep-health)
- [fasting and sleep (1)](https://info.ancsleep.com/blog/topic/fasting-and-sleep)
- [fibroids and sleep (1)](https://info.ancsleep.com/blog/topic/fibroids-and-sleep)
- [fibromyalgia (1)](https://info.ancsleep.com/blog/topic/fibromyalgia)
- [fibromyalgia and sleep (1)](https://info.ancsleep.com/blog/topic/fibromyalgia-and-sleep)
- [focus (1)](https://info.ancsleep.com/blog/topic/focus)
- [focus and sleep (1)](https://info.ancsleep.com/blog/topic/focus-and-sleep)
- [glp1 and sleep (1)](https://info.ancsleep.com/blog/topic/glp1-and-sleep)
- [gout (1)](https://info.ancsleep.com/blog/topic/gout)
- [grief (1)](https://info.ancsleep.com/blog/topic/grief)
- [grief and sleep (1)](https://info.ancsleep.com/blog/topic/grief-and-sleep)
- [gut health and sleep (1)](https://info.ancsleep.com/blog/topic/gut-health-and-sleep)
- [heart failure (1)](https://info.ancsleep.com/blog/topic/heart-failure)
- [heart health and sleep (1)](https://info.ancsleep.com/blog/topic/heart-health-and-sleep)
- [herbal remedies for sleep (1)](https://info.ancsleep.com/blog/topic/herbal-remedies-for-sleep)
- [high blood pressure and sleep (1)](https://info.ancsleep.com/blog/topic/high-blood-pressure-and-sleep)
- [hot flashes and sleep (1)](https://info.ancsleep.com/blog/topic/hot-flashes-and-sleep)
- [hypervigilence and sleep (1)](https://info.ancsleep.com/blog/topic/hypervigilence-and-sleep)
- [hypoglycemia (1)](https://info.ancsleep.com/blog/topic/hypoglycemia)
- [inflammation (1)](https://info.ancsleep.com/blog/topic/inflammation)
- [irritable bowel syndrome (1)](https://info.ancsleep.com/blog/topic/irritable-bowel-syndrome)
- [late night (1)](https://info.ancsleep.com/blog/topic/late-night)
- [learning and sleep (1)](https://info.ancsleep.com/blog/topic/learning-and-sleep)
- [learning disabilities (1)](https://info.ancsleep.com/blog/topic/learning-disabilities)
- [leg swelling (1)](https://info.ancsleep.com/blog/topic/leg-swelling)
- [light therapy (1)](https://info.ancsleep.com/blog/topic/light-therapy)
- [liver disease (1)](https://info.ancsleep.com/blog/topic/liver-disease)
- [metabolic syndrome and sleep (1)](https://info.ancsleep.com/blog/topic/metabolic-syndrome-and-sleep)
- [microsleep (1)](https://info.ancsleep.com/blog/topic/microsleep)
- [middle age (1)](https://info.ancsleep.com/blog/topic/middle-age)
- [midnight awakenings (1)](https://info.ancsleep.com/blog/topic/midnight-awakenings)
- [migraine (1)](https://info.ancsleep.com/blog/topic/migraine)
- [morning fatigue (1)](https://info.ancsleep.com/blog/topic/morning-fatigue)
- [mouthguards and sleep (1)](https://info.ancsleep.com/blog/topic/mouthguards-and-sleep)
- [multiple sclerosis (1)](https://info.ancsleep.com/blog/topic/multiple-sclerosis)
- [muscle tension and sleep (1)](https://info.ancsleep.com/blog/topic/muscle-tension-and-sleep)
- [new mother sleep (1)](https://info.ancsleep.com/blog/topic/new-mother-sleep)
- [nicotine (1)](https://info.ancsleep.com/blog/topic/nicotine)
- [night owl (1)](https://info.ancsleep.com/blog/topic/night-owl)
- [night time cramps (1)](https://info.ancsleep.com/blog/topic/night-time-cramps)
- [nighttime affirmations (1)](https://info.ancsleep.com/blog/topic/nighttime-affirmations)
- [nighttime awakenings (1)](https://info.ancsleep.com/blog/topic/nighttime-awakenings)
- [nighttime hives (1)](https://info.ancsleep.com/blog/topic/nighttime-hives)
- [nighttime itching (1)](https://info.ancsleep.com/blog/topic/nighttime-itching)
- [nighttime rumination (1)](https://info.ancsleep.com/blog/topic/nighttime-rumination)
- [nighttime worry (1)](https://info.ancsleep.com/blog/topic/nighttime-worry)
- [ocd and sleep (1)](https://info.ancsleep.com/blog/topic/ocd-and-sleep)
- [outdoor sleep (1)](https://info.ancsleep.com/blog/topic/outdoor-sleep)
- [oxytocin and sleep (1)](https://info.ancsleep.com/blog/topic/oxytocin-and-sleep)
- [parent (1)](https://info.ancsleep.com/blog/topic/parent)
- [parenting (1)](https://info.ancsleep.com/blog/topic/parenting)
- [peripheral vascular disease and sleep (1)](https://info.ancsleep.com/blog/topic/peripheral-vascular-disease-and-sleep)
- [phones and sleep (1)](https://info.ancsleep.com/blog/topic/phones-and-sleep)
- [physical activity (1)](https://info.ancsleep.com/blog/topic/physical-activity)
- [pilates and sleep (1)](https://info.ancsleep.com/blog/topic/pilates-and-sleep)
- [plmd (1)](https://info.ancsleep.com/blog/topic/plmd)
- [poor sleep (1)](https://info.ancsleep.com/blog/topic/poor-sleep)
- [posture and sleep (1)](https://info.ancsleep.com/blog/topic/posture-and-sleep)
- [progesterone and sleep (1)](https://info.ancsleep.com/blog/topic/progesterone-and-sleep)
- [protein and sleep (1)](https://info.ancsleep.com/blog/topic/protein-and-sleep)
- [psych (1)](https://info.ancsleep.com/blog/topic/psych)
- [reading and sleep (1)](https://info.ancsleep.com/blog/topic/reading-and-sleep)
- [recovery and sleep (1)](https://info.ancsleep.com/blog/topic/recovery-and-sleep)
- [remote workers (1)](https://info.ancsleep.com/blog/topic/remote-workers)
- [reproductivity and sleep (1)](https://info.ancsleep.com/blog/topic/reproductivity-and-sleep)
- [retirement and sleep (1)](https://info.ancsleep.com/blog/topic/retirement-and-sleep)
- [revenge bedtime procrastination (1)](https://info.ancsleep.com/blog/topic/revenge-bedtime-procrastination)
- [school and sleep (1)](https://info.ancsleep.com/blog/topic/school-and-sleep)
- [sciatica and sleep (1)](https://info.ancsleep.com/blog/topic/sciatica-and-sleep)
- [sedentary lifestyle and sleep (1)](https://info.ancsleep.com/blog/topic/sedentary-lifestyle-and-sleep)
- [sids (1)](https://info.ancsleep.com/blog/topic/sids)
- [sjrogrens and sleep (1)](https://info.ancsleep.com/blog/topic/sjrogrens-and-sleep)
- [sleep and appetite (1)](https://info.ancsleep.com/blog/topic/sleep-and-appetite)
- [sleep and empathy (1)](https://info.ancsleep.com/blog/topic/sleep-and-empathy)
- [sleep and executive functioning (1)](https://info.ancsleep.com/blog/topic/sleep-and-executive-functioning)
- [sleep and mood (1)](https://info.ancsleep.com/blog/topic/sleep-and-mood)
- [sleep and outlook (1)](https://info.ancsleep.com/blog/topic/sleep-and-outlook)
- [sleep and self-perception (1)](https://info.ancsleep.com/blog/topic/sleep-and-self-perception)
- [sleep and stroke (1)](https://info.ancsleep.com/blog/topic/sleep-and-stroke)
- [sleep and temperature (1)](https://info.ancsleep.com/blog/topic/sleep-and-temperature)
- [sleep and trauma (1)](https://info.ancsleep.com/blog/topic/sleep-and-trauma)
- [sleep and work (1)](https://info.ancsleep.com/blog/topic/sleep-and-work)
- [sleep doctors (1)](https://info.ancsleep.com/blog/topic/sleep-doctors)
- [sleep drive (1)](https://info.ancsleep.com/blog/topic/sleep-drive)
- [sleep inertia (1)](https://info.ancsleep.com/blog/topic/sleep-inertia)
- [sleep influencers (1)](https://info.ancsleep.com/blog/topic/sleep-influencers)
- [sleep score (1)](https://info.ancsleep.com/blog/topic/sleep-score)
- [sleepwear (1)](https://info.ancsleep.com/blog/topic/sleepwear)
- [snacks (1)](https://info.ancsleep.com/blog/topic/snacks)
- [snooze (1)](https://info.ancsleep.com/blog/topic/snooze)
- [social media and sleep (1)](https://info.ancsleep.com/blog/topic/social-media-and-sleep)
- [somniphobia (1)](https://info.ancsleep.com/blog/topic/somniphobia)
- [stimulants and sleep (1)](https://info.ancsleep.com/blog/topic/stimulants-and-sleep)
- [substance abuse and sleep (1)](https://info.ancsleep.com/blog/topic/substance-abuse-and-sleep)
- [supplements (1)](https://info.ancsleep.com/blog/topic/supplements)
- [teeth grinding at night (1)](https://info.ancsleep.com/blog/topic/teeth-grinding-at-night)
- [tension headache and sleep (1)](https://info.ancsleep.com/blog/topic/tension-headache-and-sleep)
- [tmj and sleep (1)](https://info.ancsleep.com/blog/topic/tmj-and-sleep)
- [untreated sleep apnea (1)](https://info.ancsleep.com/blog/topic/untreated-sleep-apnea)
- [vaping and sleep (1)](https://info.ancsleep.com/blog/topic/vaping-and-sleep)
- [weight gain and sleep (1)](https://info.ancsleep.com/blog/topic/weight-gain-and-sleep)
- [weighted blanket and sleep (1)](https://info.ancsleep.com/blog/topic/weighted-blanket-and-sleep)
- [wfh (1)](https://info.ancsleep.com/blog/topic/wfh)
- [worry window (1)](https://info.ancsleep.com/blog/topic/worry-window)
- [yawn (1)](https://info.ancsleep.com/blog/topic/yawn)
- [yawning (1)](https://info.ancsleep.com/blog/topic/yawning)

[see all](https://info.ancsleep.com/blog/major-considerations-for-melatonin-use#)

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